The unique molecular signature of cortical tissue injury in Multiple Sclerosis

ChEBI2011-10-05 更新2026-07-21 收录

多发性硬化分子病理学

皮质组织损伤生物标志物

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The unique molecular signature of cortical tissue injury in Multiple Sclerosis

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2011-10-05

Human brain tissues from healthy controls and multiple sclerosis patients

多发性硬化分子病理学

脑区转录组学

Multiple sclerosis (MS) is characterized by cell proliferation, migration and damage in various cell types in different CNS regions and causes disabilities related to distinct neurological pathways, s

NIAID Data Ecosystem50

Multiple sclerosis cortical normal-appearing grey matter and control grey matter

多发性硬化分子病理学

基因表达谱分析

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the brain. Among characteristics of MS pathology are cortical grey matter abnormalities, which have been linked to clinical s

NIAID Data Ecosystem30

Alterations in Neuronal Gene Expression Profiles in Response to Experimental Demyelination and Axonal Transection

多发性硬化分子病理学

元转录组分析

The pathological basis of multiple sclerosis involves damage to both myelin sheaths and axons. Demyelination and axonal transection are considered to cause reversible and irreversible neurological def

NIAID Data Ecosystem20

Expression data from periplaque regions in multiple sclerosis spinal cord. Homo sapiens

多发性硬化分子病理学

脊髓脱髓鞘转录组分析

There have been few studies that have focused on the periplaque regions surrounding demyelinated plaques, especially in spinal cords. Areas of incomplete demyelination have been demonstrated but poorl

NIAID Data Ecosystem40

Oxidative damage and respiratory burst in Multiple Sclerosis. Homo sapiens

多发性硬化分子病理学

神经退行性氧化损伤

In this project we focused on white matter injury in relapsing remitting MS. We concentrated on material obtained from patients who suffered from fulminant active MS to identify possible sources for R

NIAID Data Ecosystem30

The unique molecular signature of cortical tissue injury in Multiple Sclerosis

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