Extent of linkage disequilibrium and number of markers needed to reach average <i>r<sup>2</sup></i> = 0.1 for individual chromosomes and the whole genome.
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LD extent was computed with 43224 SNPs having MAF>0.05. aPhysical distance to reach r2 or r2s equal to 0.1 estimated using the non-linear regression implemented in r-nls obtained by fitting Hill and Weir model [53]. r2 and r2s obtained with Plink software [50] and r-LDcorSV [34], respectively. The number reported in brackets indicates the number of equidistant markers that would be needed to reach an average r2 of 0.1 between adjacent markers; bnumber of markers used to estimate LD extent for each chromosome and the whole genome.
创建时间:
2013-08-30



