STAT6 turnover

<strong>Decay of Stat6 activation in Ttc7-fsn B cells.</strong> Purified splenic B cells were stimulated with IL-4 for 30 minutes, washed 3X and allowed to rest for 15 or 30 minutes, then stained for Stat6 (red) and the nucleus (green) and imaged with confocal microscopy using a 60x objective. Co-localization of Stat6 with nucleus, denoting activation, is yellow. Ttc7fsn cells show a similar trend to WT cells at both time points, indicating they have the inherent ability to downregulate Stat6 activation when IL-4 stimulus is removed.