Transcriptome of Sod1 and Sirt2 double knock out mouse (PRJCA033760)
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https://www.ncbi.nlm.nih.gov/sra/DRP015714
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资源简介:
To investigate the effect of Sirt2 ablation in Sod1 knockout-induced progeroid mice, we found that Sirt2-/- Sod1-/- double-knockout mice exhibited a significantly reduced lifespan and pronounced progeroid phenotypes. These mice demonstrated increased expression of aging-related genes and marked immune dysregulation.
创建时间:
2025-12-07



