Pharmacokinetic parameters of darapladib following single and multiple dose administration of darapladib enteric coated tablet 160 mg once daily.

a Values are expressed as geometric mean (% geometric CV)
b Values are expressed as median (range)
Cmax = maximum plasma concentration; Tmax = Time of occurrence of Cmax; AUC(0-τ) = Area under the concentration-time curve over the dosing interval; AUC(0-∞) = Area under the concentration-time curve from time zero (pre-dose) extrapolated to infinite time; t1/2 = Terminal phase half-life; Cτ = Pre-dose (trough) concentration; NA: Not applicable; N = Number of subjects.
Pharmacokinetic parameters of darapladib following single and multiple dose administration of darapladib enteric coated tablet 160 mg once daily.