TTK is an essential spindle assembly checkpoint enzyme in many organisms. It plays a central role in tumor cell proliferation and is aberrantly overexpressed in a wide range of tumor types. We recentl
Cyclic MrIA: An exceptionally stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. Descriptor: MAI126P Authors: Lovelace, E.S, Armishaw, C.J, C
Antibiotic resistance and cancer are major global health challenges. Peptides, especially antimicrobial peptides (AMPs), have emerged as promising alternatives to conventional drugs, and some also exh
Hemp seed-derived inhibitors of dipeptidyl peptidase IV (DPP-IV) demonstrate potential as novel therapeutics for diabetes; however, their proteome and genome remain uncharacterized. We used multi-omic
Cell morphology and motility are governed largely by complex signaling networks that ultimately engage the actin cytoskeleton. Understanding how individual circuits contribute to the process of formin
