Mitochondrial genome sequencing of the HepG2 and chemo-resistant R-HepG2 cell lines. Homo sapiens isolate:HepG2

NIAID Data Ecosystem2026-03-12 收录

化疗耐药机制

线粒体测序

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA722776 数据链接链接失效反馈

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资源简介：

Mitochondrial genome sequencing was performed with the HepG2 and its chemo-resistant mutant, R-HepG2, to identify mutations related to chemo-resistance.

创建时间：

2021-04-18

Gene expression profile of patient-derived head and neck squamous carcinoma cells subjected to different treatments.. Gene expression profile of patient-derived head and neck squamous carcinoma cells subjected to different treatments.

头颈部鳞状细胞癌基因

化疗耐药机制

In order to investigate the mechanisms underlying response and resistance towards treatment in HNSCC, we used low passage in vitro HNSCC cultures from two patients, namely SJG26 and SJG17. Both cultur

NIAID Data Ecosystem70

Loss of IFN-g signaling in tumor cells associates with primary resistance to anti-CTLA-4 therapy

化疗耐药机制

IFN-γ信号通路

"Antibody blockade of the inhibitory CTLA-4 pathway has led to clinical benefit in a subset of patients with metastatic melanoma. Anti-CTLA-4 enhances T cell responses, including production of IFN-?,

NIAID Data Ecosystem40

DataSheet9_Therapeutic Suppression of FAK-AKT Signaling Overcomes Resistance to SHP2 Inhibition in Colorectal Carcinoma.ZIP

化疗耐药机制

AKT信号通路

SHP2 mediates signaling from multiple receptor tyrosine kinases (RTKs) to extracellular signal-regulated kinase (ERK) and Ser and Thr kinase AKT, and its inhibitors offer an unprecedented opportunity

NIAID Data Ecosystem10

Raw data for the mitochondrial genome of the scarlet-backed flowerpecker (Dicaeum cruentatum)

系统发育

线粒体测序

To help with the phylogenetic studies of Dicaeum species, the complete mitochondrial sequences of D. cruentatum were sequenced using the next generation sequencing platform. The DNA library was constr

NIAID Data Ecosystem50

Unveiling alterations of epigenetic modifications and chromatin architecture leading to lipid metabolic reprogramming during the evolutionary trastuzumab adaptation of HER2-positive breast cancer [Cut & Tag]. Unveiling alterations of epigenetic modifications and chromatin architecture leading to lipid metabolic reprogramming during the evolutionary trastuzumab adaptation of HER2-positive breast cancer [Cut & Tag]

化疗耐药机制

表观遗传调控

Secondary trastuzumab resistance represents an evolutionary adaptation of HER2-positive breast cancer during anti-HER2 treatment. Most current studies have uncovered the alternations of HER2 and assoc

NIAID Data Ecosystem20

Mitochondrial genome sequencing of the HepG2 and chemo-resistant R-HepG2 cell lines. Homo sapiens isolate:HepG2

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