More than just a pretty face? The relationship between immune function and perceived facial attractiveness

It has long been hypothesized that attractiveness provides a cue to a
target’s health and immunocompetence. However, much of the research
testing this hypothesis has relied on a small number of indirect proxies
of immune function and the results of this research have been mixed. Here,
we build on this past research, examining the relationship between target
attractiveness and: (a) self-reported health, (b) in vivo measures of
inflammation and white blood cell count / composition, and (c) in vitro
tests of targets’ immune function, including (c1) leukocyte proliferation
in response to immunological stimulants, (c2) phagocytosis of Escherichia
coli bioparticles, (c3) NK cell-mediated lysis of target tumor cells, and
(c4) Staphylococcus aureus growth in isolated plasma. Results revealed
multiple, sometimes sex-differentiated, relationships between targets’
immune function and others’ perceptions of their attractiveness. Together,
this work suggests complex, often sex-differentiated relationships between
immune function, health, and attractiveness.