Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 2
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Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 2 Descriptor: (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(cyclohexylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA Authors: Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. Deposit date: 2012-05-25 Release date: 2012-08-22 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
2009年甲型H1N1流感病毒(Influenza strain pH1N1 2009)聚合酶PA亚基核酸内切酶(endonuclease)与二酮化合物2的复合物
组分描述:(Z)-4-[4-[(4-氯苯基)甲基]-1-(环己基甲基)哌啶-4-基]-2-羟基-4-氧代-2-丁烯酸、锰(II)离子、聚合酶PA
作者:Kowalinski, E、Zubieta, C、Wolkerstorfer, A、Szolar, O.H、Ruigrok, R.W、Cusack, S
沉积日期:2012-05-25
发布日期:2012-08-22
最后修改日期:2023-12-20
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.2埃(Å)
引用文献:《靶向2009年甲型H1N1流感病毒聚合酶核酸内切酶结构域的特异性金属螯合抑制剂结合结构分析》(*Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase*),发表于*Plos Pathog.*,2012年,第8卷
创建时间:
2012-05-25



