Resveratrol improves liver steatosis and insulin resistance in non-alcoholic fatty liver disease in association with the gut microbiota

16S rRNA gene sequencing The mice were randomly divided into 3 groups: the NC, HFD and RSV groups. The NC group (n=5) was fed a normal chow diet. The HFD group (n=6) and RSV group (n=8), In the first 8 weeks, the HFD and RSV groups were maintained under the same conditions to establish the NAFLD model. Thereafter, the RSV group underwent oral gavage with resveratrol daily for the last 4 weeks,