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RNA-seq of transgenic Anopheles gambiae MM-CP midguts

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NIAID Data Ecosystem2026-03-13 收录
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We augmented the Zinc carboxypeptidase A1 (CP, AGAP009593) gene of the malaria mosquito Anopheles gambiae to secrete the exogenous antimicrobial peptides Magainin 2 and Melittin, and to enable non-autonomous gene drive via an intronic guide RNA. We performed RNA-seq on dissected midguts prior to and 6 and 20 hours after blood feeding in parallel with the wild-type.

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2022-05-06
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