RNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance

The Saccharomyces cerevisiae TRAMP4 and TRAMP5 complexes, which consist of the poly(A) polymerase Trf4 or Trf5, respectively, the zinc knuckle proteins Air1 or Air2, and the RNA helicase Mtr4, play a critical role in nuclear RNA surveillance酿酒酵母（Saccharomyces cerevisiae）的TRAMP4与TRAMP5复合物，分别由聚(A)聚合酶Trf4或Trf5、锌指蛋白Air1或Air2，以及RNA解旋酶Mtr4组成，在细胞核RNA监视过程中发挥关键作用。