Single-cell sequencing of colorectal cancer liver metastases

Cancer cells and fibroblasts from 6 metastases obtained from 5 different patients were submitted to single-cell sequencing on the 10xGenomics platform. These data revealed different subpopulations of cancer-associated fibroblasts (CAF) and their ligand-receptor interactions with cancer cells. Overall design: Single-cell sequencing of colorectal cancer liver metastases cancer cells and fibroblasts.