Global Gene Expression Fails to Discriminate Thin Melanomas with Poor Outcomes. Homo sapiens

Melanoma is the fifth-most common cancer diagnosed in the United States with a dramatic increase in incidence among both men and women. Most melanomas present as thin lesions (≤1.0mm) and have a good prognosis. However a small percentage of patients (5-10%) with thin lesions recur or metastasize. The aim of our study was to elucidate which thin melanomas (10 years with no recurrence) to those that eventually metastasized either to regional lymph nodes or distantly.