Crystal structure of human Cathepsin-S with bound ligand

Crystal structure of human Cathepsin-S with bound ligand Descriptor: (4~{S})-1-[1-[(2~{S})-3-[3-[3-[2-(4-methylpiperidin-1-yl)ethylsulfanyl]-4-(trifluoromethyl)phenyl]-5-methylsulfonyl-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-1-yl]-2-oxidanyl-propyl]piperidin-4-yl]-4-oxidanyl-pyrrolidin-2-one, Cathepsin S Authors: Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-08-04 Release date: 2017-12-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of human Cathepsin-S with bound ligand To be published人组织蛋白酶S（Cathepsin S）结合配体的晶体结构 配体描述符：(4S)-1-[1-[(2S)-3-[3-[3-[2-(4-甲基哌啶-1-基)乙硫基]-4-(三氟甲基)苯基]-5-甲磺酰基-6,7-二氢-4H-吡唑并[4,3-c]吡啶-1-基]-2-羟基丙基]哌啶-4-基]-4-羟基吡咯烷-2-酮 作者：Bembenek S.D.、Ameriks M.K.、Mirzadegan T.、Yang H.、Shao C.、Burley S.K. 提交日期：2017-08-04 发布日期：2017-12-20 最后修改日期：2024-11-06 测试方法：X射线衍射（分辨率2.1埃） 引用说明：人组织蛋白酶S结合配体的晶体结构，待发表