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Multi-modal skin atlas associates a multicellular immune-stromal community with altered cornification and T cell expansion in atopic dermatitis.

NIAID Data Ecosystem2026-05-02 收录

特应性皮炎

皮肤免疫图谱

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE204765 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-05-13

药物研发

特应性皮炎

Additional file 1: Supplementary data. A novel sphingosylphosphorylcholine and sphingosine-1-phosphate receptor 1 antagonist, KRO-105714, for alleviating atopic dermatitis. Supplementary figure 1. NMR

DataCite Commons2020-08-25 更新130

Amygdalin alleviates atopic dermatitis-like skin inflammation via inhibition of Th2 immune responses

特应性皮炎

免疫调节

Atopic dermatitis (AD) is a chronic skin disease marked by immune dysregulation such as upregulated T helper (Th) 2 responses. While Th2-targeted therapies for AD are under development, their applicat

DataCite Commons2025-09-29 更新110

Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

特应性皮炎

骨髓增殖性疾病

BackgroundThe Notch pathway is essential for proper epidermal differentiation during embryonic skin development. Moreover, skin specific loss of Notch signaling in the embryo results in skin barrier d

NIAID Data Ecosystem60

Additional file 9: Table E5. of Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

特应性皮炎

基因表达分析

Khattri 2014 (GSE58558) – Ingenuity Pathway Analysis. (XLSX 26 kb)

DataCite Commons2024-12-18 更新120

A Phase 2 Randomized Trial of Apremilast in Patients With Atopic Dermatitis. A Phase 2 Randomized Trial of Apremilast in Patients With Atopic Dermatitis

特应性皮炎

药物安全性评估

A phase 2, double-blind, placebo-controlled trial evaluated apremilast efficacy, safety, and pharmacodynamics in adults with moderate to severe atopic dermatitis (AD). Overall design: Patients were ra

NIAID Data Ecosystem100

Multi-modal skin atlas associates a multicellular immune-stromal community with altered cornification and T cell expansion in atopic dermatitis.

资源简介：

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