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Pharmacogenomic characterization of the MDM2 inhibitor MI-773 reveals candidate tumours and predictive biomarkers. Pharmacogenomic characterization of the MDM2 inhibitor MI-773 reveals candidate tumours and predictive biomarkers

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA639587
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MI-773 is a recently developed small-molecule inhibitor of the Mouse Double Minute 2 (MDM2) proto-oncogene. Here we report an integrative pharmacogenomic study to gain further insights into the therapeutic potential of the compound. Overall design: Total RNA samples were extracted using the mirVana kit (Ambion) following the manufacturer's recommendations. After standard quality controls RNA were subjected to Affymetrix HGU133 Plus2.0 microarray hybridization.
创建时间:
2020-06-15
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