Effects of Ketamine on Postoperative Cognition: A Scoping Review Dataset

This dataset was compiled to investigate the effects of ketamine on postoperative cognitive function in human study participants. It comprises data from 58 clinical trials and retrospective cohort analyses that were published prior to 2025-Feb-15 and met two key criteria: (1) administration of racemic (R,S) ketamine, esketamine, or arketamine to adult surgical patients, and (2) reporting of postoperative cognitive evaluation. Data points for each study include aspects of study design, patient demographic characteristics, surgical procedures, ketamine administration protocols, and the methods and outcomes of cognitive assessment.本数据集旨在探究氯胺酮对人类研究受试者术后认知功能的影响。其收录了截至2025年2月15日已发表的58项临床试验与回顾性队列分析数据，所有纳入研究均满足两项核心标准：其一，向成年手术患者给予消旋（R,S）氯胺酮（racemic (R,S) ketamine）、艾司氯胺酮（esketamine）或阿氯胺酮（arketamine）；其二，报告了术后认知评估相关内容。每项研究的相关数据项涵盖研究设计、患者人口统计学特征、手术操作流程、氯胺酮给药方案，以及认知评估的方法与结局。