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Lattice kinetic Monte Carlo model to simulate RNA polymerase II clusters during stem cell differentiation

NIAID Data Ecosystem2026-05-01 收录

RNA聚合酶II簇模拟

细胞分化转录调控

数据链接：

https://zenodo.org/record/7966556 数据链接链接失效反馈

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资源简介：

This data set includes Python scripts (numerical simulation and analysis) and already generated simulation data for RNA polymerase II clusters during stem cell differentiation. It includes the whole data to recreate panels.

应用场景：

创建时间：

2023-05-25

RNA结合蛋白功能

细胞分化转录调控

Background: Cellular RNA binding proteins (RBPs) have multiple roles in post-transcriptional control, and some have been shown to bind DNA. However, the global localization and the general chromatin-b

NIAID Data Ecosystem60

Genome-wide profiling of PPAR?:RXR and RNA polymerase II

细胞分化转录调控

代谢途径基因

Genome-wide profiling of PPAR?:RXR and RNA polymerase II reveals temporal activation of distinct metabolic pathways in RXR dimer composition during adipogenesis. Chromatin immunoprecipitation combined

NIAID Data Ecosystem40

The RNA exosome contributes to gene expression regulation during stem cell differentiation [CAGE]. The RNA exosome contributes to gene expression regulation during stem cell differentiation [CAGE]

细胞分化转录调控

RNA外泌体介导的RNA衰变

Gene expression programs change during cellular transitions. It is well established that a network of transcription factors and chromatin modifiers regulate RNA levels during embryonic stem cell (ESC)

NIAID Data Ecosystem30

GRO-seq in mouse Epiblast-primed, Primitive endoderm-primed, and differentiated endoderm cells

细胞分化转录调控

胚胎发育转录组学

The identification of changes in transcriptional regulation during priming and differentiation of embryonic stem (ES) cells towards the endoderm lineage. Specific populations of ES cells, either prime

NIAID Data Ecosystem50

Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features [dataset 2]

染色质动力学

细胞分化转录调控

3D chromatin structure is thought to play a critical role in regulating gene transcription during cellular transitions. While our understanding of loop formation and maintenance is rapidly improving,

NIAID Data Ecosystem30

Lattice kinetic Monte Carlo model to simulate RNA polymerase II clusters during stem cell differentiation

资源简介：

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