BackgroundParaoxonase-1 (PON1) is an antioxidant enzyme, that resides on high-density lipoprotein (HDL). PON1-activity, is heavily influenced by the PON1-Q192R polymorphism. PON1 is considered to prot
BackgroundCoronary heart disease (CHD) is the most common cause of death worldwide. Previous studies have identified numerous common CHD susceptibility loci, with the vast majority identified in popul
BackgroundThe polymorphism of plasminogen activator inhibitor-1 (PAI-1) 4G/5G gene has been indicated to be correlated with coronary artery disease (CAD) susceptibility, but study results are still de
HTN:hypertension; DM:diabetes mellitus; BMI:body mass index; Age and BMI were considered as continuous variables. a:P values for significance of covariates in the pooled genetic effect.