Ru-Catalyzed Rearrangement of N‑Methyl Isoxazolidines to N–H 1,3‑Oxazinanes: A Strategy of Self-Hydride Transferring Cleavage of N–O Bonds

A strategy of ruthenium-catalyzed self-hydride transferring cleavage of N–O bonds was designed and utilized in a cascade 1,3-dipolar cyclization of alkenes and N-methyl nitrones followed by an N-demethylative rearrangement, furnishing synthetically useful N–H 1,3-oxazinanes.