Beta-blocker Stratification using MRI to assess portal pressure (B-SMaRT)

Beta-blocker Stratification using quantitative MRI techniques to assess portal pressure and Response to Treatment in patients with portal hypertension (B-SMaRT study). To provide proof of concept that quantitative haemodynamic MRI markers can stratify the efficacy of carvedilol to lower clinically significant portal hypertension in patients with cirrhosis. Descriptive sequential pilot study of patients with cirrhosis, portal pressure measurement, research MRI (at 3T) and endoscopy with outcomes with repeat measures in those who are given Carvedilol.