FEATURES OF THE CLINICAL COURSE AND THE STATE OF PHYSICAL AND NEUROPSYCHOLOGICAL STATUS IN CHILDREN WITH THE NATURAL COURSE OF ATRIAL SEPTAL DEFECT

Isolated atrial septal defect (ASD) is one of the most common forms of congenital septal heart anomalies. The key factors determining the clinical course and hemodynamic disturbances in ASD are a persistent left-to-right shunt, which leads to pulmonary overcirculation and pulmonary hypertension (PH), as well as dysfunction of the pulmonary vasculature, resulting in the development of heart failure