Upon vascular injury, circulating von Willebrand factor (VWF) binds to exposed vascular collagen. This Reactome event shows defective binding of VWF to collagen type I caused by loss-of-function mutat

reactome.org100

Main haemostatic pattern of the type 2B VWD patients studied characterized by normal VWF multimer pattern.

血管性血友病

VWF血管性血友病因子

Main haemostatic pattern of the type 2B VWD patients studied characterized by normal VWF multimer pattern.

NIAID Data Ecosystem40

Defective binding of VWF variant to GPIb:IX:V

血管性血友病

凝血机制

This Reactome event describes von Willebrand disease (VWD)-associated missense mutations in the A1 domain of VWF, namely VWF S1358N, S1387I, S1394F and Q1402P, that compromise the clot formation due t

reactome.org40

Main haemostatic findings of the VWD patients studied characterized by VWF functional abnormalities.

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Main haemostatic findings of the VWD patients studied characterized by VWF functional abnormalities.

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