THE SIGNIFICANCE OF RISK FACTORS AND NUTRITIONAL STATUS IN THE DEVELOPMENT OF KIDNEY STONE DISEASE

This thesis examines the mechanisms underlying the development of kidney stone disease (nephrolithiasis), its major risk factors, types of urinary stones, clinical manifestations, and preventive measures. Urinary supersaturation, reduced concentrations of crystallization inhibitors, and impaired urinary flow are identified as key factors contributing to stone formation. The importance of adequate fluid intake and appropriate dietary habits in reducing the risk of disease recurrence is also discussed.