turmex2/pgc-ocd-tourette

--- license: other tags: - gwas - polygenic-risk-score - psychiatric-genetics - pgc --- # Obsessive-Compulsive Disorder GWAS Summary Statistics (PGC) Mirror of Psychiatric Genomics Consortium (PGC) summary statistics for **Obsessive-Compulsive Disorder** (ocd2025), redistributed in a single Apache Parquet file for use with [OpenMed Genomics](https://huggingface.co/spaces/turmex2/openneuro-genomics). ## Source - **Primary citation:** International OCD Foundation Genetics Collaborative, 2025 - **Original distributor:** Psychiatric Genomics Consortium (<https://pgc.unc.edu/for-researchers/download-results/>) This mirror exists only because the upstream OpenMed mirror became inaccessible. No modifications have been made to the underlying data; per-shard parquet files were concatenated into a single file for convenient streaming. ## File `pgc-ocd-tourette_ocd2025.parquet` -- one Apache Parquet file containing the full summary statistics table in the PGC's published schema (SNP, CHR, BP, A1, A2, FRQ, OR/BETA, SE, P, ...). ## Usage ```python import polars as pl df = pl.read_parquet( "https://huggingface.co/datasets/turmex2/pgc-ocd-tourette/resolve/main/pgc-ocd-tourette_ocd2025.parquet" ) ``` ## License & terms of use PGC summary statistics are released for non-commercial research use only. Do not attempt to re-identify individuals. Results derived from these data are **not** a clinical diagnosis. See the original publication for the full data-use agreement.license: 其他许可 tags: - 全基因组关联研究（Genome-Wide Association Study, GWAS） - 多基因风险评分（Polygenic Risk Score） - 精神遗传学（Psychiatric Genetics） - 精神疾病基因组学联盟（Psychiatric Genomics Consortium, PGC） # 强迫症全基因组关联研究汇总统计数据集（PGC版） 本数据集为精神疾病基因组学联盟（Psychiatric Genomics Consortium, PGC）针对**强迫症（Obsessive-Compulsive Disorder, OCD）**（数据集版本号ocd2025）的汇总统计数据镜像，已整合为单个Apache Parquet文件，适配[OpenMed Genomics](https://huggingface.co/spaces/turmex2/openneuro-genomics)工具链使用。 ## 数据来源 - **核心引用文献**：国际强迫症基金会遗传学协作组，2025年 - **原始发布方**：精神疾病基因组学联盟（<https://pgc.unc.edu/for-researchers/download-results/>） 本镜像仅因上游OpenMed镜像无法访问而创建，未对原始数据进行任何修改；仅将分块的Parquet文件合并为单个文件，以方便流式读取。 ## 数据文件 `pgc-ocd-tourette_ocd2025.parquet` —— 单个Apache Parquet文件，包含遵循PGC发布规范的完整汇总统计数据表，字段包括SNP、染色体号（CHR）、碱基位置（BP）、效应等位基因（A1）、非效应等位基因（A2）、等位基因频率（FRQ）、比值比/回归系数（OR/BETA）、标准误（SE）、P值（P）等。 ## 使用示例 python import polars as pl df = pl.read_parquet( "https://huggingface.co/datasets/turmex2/pgc-ocd-tourette/resolve/main/pgc-ocd-tourette_ocd2025.parquet" ) ## 许可与使用条款 PGC汇总统计数据仅可用于非商业性科研用途。请勿尝试重新识别个体。基于本数据得到的结果**不得**作为临床诊断依据。完整数据使用协议请参阅原始发表文献。