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FABP5 aggravates lipid metabolism to facilitate pancreatic neuroendocrine neoplasms progression via FASN mediated Wnt/beta-catenin pathway

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NIAID Data Ecosystem2026-03-14 收录
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This study showed that FABP5 might play a role of oncogene through playing an auxo-action for the deposition of lipid droplets and FABP5 is involved in activating the Wnt/beta-catenin pathway. Moreover, those carcinogenic effects of FABP5 can be reversed by orlistat, providing novel choice for therapeutic intervention.

创建时间:
2023-01-03
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