Data related to manuscript: BET protein inhibitor JQ1 reduces inflammation and hippocampal amyloid-β level without altering Tau phosphorylation in LPS-challenged adult wild-type mice

Data related to manuscript: BET protein inhibitor JQ1 reduces inflammation and hippocampal amyloid-β level without altering Tau phosphorylation in LPS-challenged adult wild-type mice.These data were used to create Figures 1-6.Figure 1 presents the effect of JQ1 on sickness behavior after LPS-evoked systemic inflammation in mice up to 12 h post-injection.Figure 2 presents the effect of JQ1 on cytokine levels in blood serum 3 and 12 h after LPS-evoked systemic inflammation.Figure 3 presents the effect of LPS-evoked systemic inflammation on the level of BET proteins in the murine hippocampus 12 h post-injection.Figure 4 presents the effect of LPS and JQ1 on the expression of inflammation-related genes in hippocampus 3 and 12 h post-injection.Figure 5 presents the effect of JQ1 on Tau level and phosphorylation in the hippocampus 12 h after LPS-evoked systemic inflammation.Figure 6 presents the effect of JQ1 on Amyloid-β level in the hippocampus 12 h after LPS-evoked systemic inflammation.Figure 7 presents the effect of JQ1 on the expression of inflammation-related genes in hippocampus 3 and 12 h post-injection.