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Unusual Dimeric Chemical Structure for a Carboplatin Analogue as a Potential Anticancer Complex

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NIAID Data Ecosystem2026-03-06 收录
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An unexpected and unusual dimeric platinum(II) tetracarboxylate complex was obtained by the reaction of cis-[Pt(NH3)2I2] with disilver dicarboxylate. The complex exhibits greater in vitro anticancer activity and lower toxicity in mice than its parent compound, carboplatin, and is therefore worthy of further evaluation as a potential antitumor dinuclear platinum agent.

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2016-02-24
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