HGTree

The HGTree database provides putative genome-wide horizontal gene transfer (HGT) information for 2,472 completely sequenced prokaryotic genomes. HGT detection is based on an explicit evolutionary model of tree reconstruction and relies on evaluating the conflicts between phylogenetic tree of each orthologous gene set and corresponding 16S rRNA species tree. The database provides quick and easy access to HGT-related genes in hundreds of prokaryotic genomes and provides functionalities to detect HGT in user-customized datasets and gene and genome sequences. The database is freely available and can be easily scaled and updated to keep pace with the rapid rise in genomic information.HGTree数据库为2472个完成全基因组测序的原核生物基因组提供全基因组范围的潜在水平基因转移（horizontal gene transfer, HGT）信息。其HGT检测基于一套明确的系统发育树构建进化模型，通过比对每个直系同源基因集的系统发育树与对应16S rRNA物种树之间的冲突情况完成检测。该数据库支持用户快速便捷地检索数百个原核生物基因组中的HGT相关基因，同时提供针对用户自定义数据集、基因序列及基因组序列的HGT检测功能。本数据库免费对外开放，且可轻松扩容更新，以紧跟基因组信息快速增长的发展步伐。

搜集汇总

背景与挑战

背景概述

HGTree数据库是一个水平基因转移（HGT）信息库，涵盖2,472个已测序原核生物基因组，通过比较基因树与物种树的冲突来检测HGT事件。该数据库提供多种在线分析工具，允许用户进行基因组间HGT分析，并支持下载相关序列和统计信息。