Inverted repeat structure of the Sry locus in mice.
收藏PubMed Central1992-09-01 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC49833/
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资源简介：
The testis-determining gene Sry is located on the short arm of the mouse Y chromosome in a region known to have undergone duplications and rearrangements in comparison with the equivalent portion of the human Y chromosome. Detailed analysis of the Sry genomic locus reveals a further difference in that the mouse Sry open reading frame lies within 2.8 kilobases of unique sequence at the center of a large inverted repeat. This repeat, which is found in both Mus musculus musculus and Mus musculus domesticus Y chromosomes, is not present at the human SRY locus. Recombination involving the repeat region may have led to an 11-kilobase deletion, precisely excising Sry in a line of XY female mice. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1992-09-01
