Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
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Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ... Authors: Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. Deposit date: 2020-10-26 Release date: 2021-03-17 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
含奈韦拉平(nevirapine)的HIV-1逆转录酶(HIV-1 reverse transcriptase)起始复合物核心结构
描述符:11-环丙基-5,11-二氢-4-甲基-6H-二吡啶并[3,2-B:2',3'-E][1,4]二氮杂卓-6-酮、HIV-1病毒RNA片段、镁离子(Magnesium Ion)等
作者:Ha B、Larsen K.P、Zhang J、Fu Z、Montabana E、Jackson L.N、Chen D.H、Puglisi E.V.
存入日期:2020-10-26
发布日期:2021-03-17
最后修改日期:2024-10-23
研究方法:电子显微镜(分辨率3.1埃(Å))
引用文献:《HIV-1逆转录酶起始复合物的高分辨率观测及非核苷类逆转录酶抑制剂(Non-Nucleoside Reverse Transcriptase Inhibitor,NNRTI)类药物的抑制作用》,《自然-通讯(Nature Communications,缩写Nat Commun)》,第12卷,2021年
创建时间:
2020-10-26



