High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to YM2-059

High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to YM2-059 Descriptor: Tyrosine-protein kinase JAK2, [3-(4-{2-[3,5-difluoro-4-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)-1-(ethanesulfonyl)azetidin-3-yl]acetonitrile Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-07-12 Release date: 2021-09-01 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.38 Å) Cite: High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to YM2-059. To Be Published结合YM2-059的人JAK2激酶结构域（JH1）高分辨率晶体结构 描述：酪氨酸蛋白激酶JAK2，[3-(4-{2-[3,5-二氟-4-(1-甲基-1,2,3,6-四氢吡啶-4-基)苯胺基]-7H-吡咯并[2,3-d]嘧啶-4-基}-1H-吡唑-1-基)-1-(乙磺酰基)氮杂环丁烷-3-基]乙腈 作者：Karim, M.R.、Schonbrunn, E. 提交日期：2021-07-12 发布日期：2021-09-01 最后修改日期：2024-11-13 实验方法：X射线衍射（1.38 Å） 引用信息：结合YM2-059的人JAK2激酶结构域（JH1）高分辨率晶体结构，待发表