half_life_obach

## Dataset Details

### Dataset Description

Half life of a drug is the duration for the concentration of the drug
in the body to be reduced by half. It measures the duration of actions of a drug.
This dataset deposited version under CHEMBL assay 1614674.

- **Curated by:**
- **License:** CC BY 4.0

### Dataset Sources

- [corresponding publication](https://doi.org/10.1124/dmd.108.020479)
- [data source](https://tdcommons.ai/single_pred_tasks/adme/#half-life-obach-et-al)

## Citation

**BibTeX:**

```bibtex
@article{Obach2008,
doi = {10.1124/dmd.108.020479},
url = {https://doi.org/10.1124/dmd.108.020479},
year = {2008},
month = apr,
publisher = {American Society for Pharmacology and Experimental Therapeutics (ASPET)},
volume = {36},
number = {7},
pages = {1385--1405},
author = {R. Scott Obach and Franco Lombardo and Nigel J. Waters},
title = {Trend Analysis of a Database of Intravenous Pharmacokinetic
Parameters in Humans for 670 Drug Compounds},
journal = {Drug Metabolism and Disposition}
```

## 数据集详情

### 数据集描述
药物半衰期（half life）指药物在体内浓度降低至初始浓度一半所需的时长，可用于表征药物在体内的作用持续时长。本数据集的存档版本隶属于CHEMBL测定编号1614674。

- **数据整理者：**
- **授权协议：** CC BY 4.0

### 数据集来源
- [相关研究文献](https://doi.org/10.1124/dmd.108.020479)
- [数据来源](https://tdcommons.ai/single_pred_tasks/adme/#half-life-obach-et-al)

## 引用信息

**BibTeX格式引用：**
bibtex
@article{Obach2008,
doi = {10.1124/dmd.108.020479},
url = {https://doi.org/10.1124/dmd.108.020479},
year = {2008},
month = {四月},
publisher = {美国药理与实验治疗学会（ASPET)},
volume = {36},
number = {7},
pages = {1385--1405},
author = {R·斯科特·奥巴奇、佛朗哥·隆巴尔多、奈杰尔·J·沃特斯},
title = {670种药物化合物人体静脉给药药代动力学参数数据库的趋势分析},
journal = {《药物代谢与处置》（Drug Metabolism and Disposition)}
}