GsMTx4 suppresses pro-inflammatory gene expression in DSS-induced colitis in mice.
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https://www.ncbi.nlm.nih.gov/sra/SRP402654
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资源简介：
The spider venom-derived peptide GsMTx4 specifically inhibits mechanosensory ion channels. It has been reported that GsMTx4 plays an immunoregulatory role in several inflammatory conditions. Therefore, we administrated GsMTx4 to mice with dextran sodium sulfate (DSS)-induced acute colitis, to explore whether it regulates inflammatory responses in colitis. Overall design: 8-week-old mice were administered 2.5% DSS (MP Biologicals) in drinking water for 7 consecutive days, with intravenous injection of GsMTx4 (10 mg/kg, Alomone Labs) or solvent on days 2, 4, and 6. Mice given normal drinking water were used as Control group.
创建时间：
2023-10-16
