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Identification and genetic dissection of convergent persister cell states

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP432059
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We generated a high-resolution single-cell RNA atlas of E. coli growth transitions, which revealed that a distinct persister state. We then used ultra-dense CRISPR-interference to determine how every E. coli gene contributes to persister formation across genetic models. ***Download data version 2 whenever present*** Overall design: scRNA-seq of E. coli cells using PETRI-seq method; CRISPRi screen of E. coli cells
创建时间:
2025-01-03
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