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Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal and malignant urothelial cells

NIAID Data Ecosystem2026-05-02 收录

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ARID1A基因调控机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE271687 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-06-03

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靶向测序

We analyzed data from over 600 patients and demonstrated that the combination of ARID1A loss and high CD8 + T cell infiltration defines a distinct subgroup of urothelial carcinoma (UC) with

Figshare2025-07-11 更新100

Non-invasive diagnosis of urothelial cancer in urine using DNA hypermethylation signatures

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甲基化DNA生物标志物

Methylation status of free DNA from urine from patients with urothelial tumor and healthy control patients were analysed Patients with histologically confirmed urothelial cancer vs healthy control don

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Cutoff values for each of the studied genes.

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β2-整合素生物标志物

β2-integrins are a family of adhesion proteins expressed in immune cells that play multiple roles in anti-tumor immunity. β2-integrins regulate tumor infiltration of anti-tumorigenic immune cells such

Figshare2025-10-24 更新30

放射治疗

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This record contains raw data related to article "Stereotactic Body Radiation Therapy in the Management of Oligometastatic and Oligoprogressive Bladder Cancer and Other Urothelial Malignancies" Aims

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Dataset from A Phase II Single Arm Clinical Trial of Nivolumab (BMS-936558) in Subjects With Metastatic or Unresectable Urothelial Cancer Who Have Progressed or Recurred Following Treatment With a Platinum Agent

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肿瘤缩小效果评估

The purpose the study is to measure the effect of nivolumab (BMS-936558) in reducing tumor size in subjects with metastatic or unresectable bladder cancer.

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Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal and malignant urothelial cells

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