RNA-Seq analysis of LYN deficient HS-5 stroma cells cocultured with primary human CLL cells

ChEBI2023-02-10 更新2026-07-12 收录

肿瘤微环境转录组

淋巴细胞白血病分子机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12629 数据链接链接失效反馈

官方服务：

资源简介：

RNA-Seq analysis of LYN deficient HS-5 stroma cells cocultured with primary human CLL cells

创建时间：

2023-02-10

Aberrant RNA expression and splicing in childhood ETV6/RUNX1 acute lymphoblastic leukemia. Aberrant RNA expression and splicing in childhood ETV6/RUNX1 acute lymphoblastic leukemia

淋巴细胞白血病分子机制

儿童恶性肿瘤转录组学

ETV6/RUNX1 E/R -positive acute lymphoblastic leukemia (ALL), as one of the most common childhood malignancies, its pathogenesis and mechanism remain to be elucidated comprehensively. Global gene expre

NIAID Data Ecosystem60

Mus musculus Raw sequence reads

肿瘤微环境转录组

细胞应激响应

We compared normally cultured LLC cells (NT) with LLC cultured in CM from unstressed M-BMDM (CM_M0) or GM-BMDM (CM_G0) as well as with LLC cultured in CM from 12 hours-ER stressed M-BMDM (CM_M12) or G

NIAID Data Ecosystem30

RBPJ and H3K27ac chromatin IP with sequencing of CLL cells with hyperactivated Notch1 compared to control CLL cells [ChIP-seq]. RBPJ and H3K27ac chromatin IP with sequencing of CLL cells with hyperactivated Notch1 compared to control CLL cells [ChIP-seq]

淋巴细胞白血病分子机制

Notch信号通路

NOTCH1 gain-of-function mutations are recurrent in B cell chronic lymphocytic leukemia (B-CLL), where they are associated with accelerated disease progression and refractoriness to chemotherapy. The s

NIAID Data Ecosystem30

Bulk RNA-seq profiling of cancer-associated fibroblast co-culture systems reveals subtype-specific transcriptional programs

肿瘤微环境转录组

癌症相关成纤维细胞信号传导

This project includes bulk RNA sequencing data generated from tumor organoid co-culture systems incorporating cancer-associated fibroblasts (CAFs) and immune cell populations. The study aims to charac

NIAID Data Ecosystem40

Bulk RNA-seq of Fibroblastic Reticular Cells

肿瘤微环境转录组

成纤维网状细胞功能

Fibroblastic reticular cells (FRCs) (CD45- Ter119-MADCAM1- CD21/35- CD31- PDPN-) from skin draining lymph nodes of Grem1-Cre-ERT2.cki; Rosa26-LSL-EYFP mice were sorted and subjected to bulk RNA-seq of

NIAID Data Ecosystem30

RNA-Seq analysis of LYN deficient HS-5 stroma cells cocultured with primary human CLL cells

资源简介：

相关数据集