Systemic Complications of Streptococci in Chronic Tonsillitis: Case Series

Streptolysin O is one of the toxins produced from Group A Beta Hemolytic Streptococcal (GABHS) infection. In the human body infected with GABHS will produce a natural antigen, namely anti-Streptolysin titer O (ASTO). [1] Throat culture is performed to determine the presence of group A Streptococci in the upper respiratory tract. Throat cultures have a sensitivity of about 90% - 95% in detecting the presence of GABHS. The purpose of writing this case report is to provide knowledge to peers about systemic complications resulting from Streptococcal infection in tonsillitis. It has been reported in all five cases mentioned above with an increase in ASTO titer >200 IU/ml. Of the five patients experienced complications due to Streptolysin toxin, endophtalmitis, rheumatoid arthritis and endocarditis. While from the examination of tonsil culture found Candida sp., Enterococcus faecalis, Enterobacter aerogenes.链球菌溶血素O（Streptolysin O）是A组β溶血性链球菌（Group A Beta Hemolytic Streptococcal, GABHS）感染所产生的毒素之一。感染A组β溶血性链球菌的人体会产生天然抗原，即抗链球菌溶血素O滴度（anti-Streptolysin titer O, ASTO）[1]。咽喉培养可用于检测上呼吸道中是否存在A组链球菌。咽喉培养对A组β溶血性链球菌的检测灵敏度约为90%~95%。撰写本病例报告的目的，在于向同行分享链球菌感染引发扁桃体炎后所导致的全身并发症相关知识。上述5例病例均报告抗链球菌溶血素O滴度＞200 IU/ml。5例患者均出现由链球菌溶血素毒素引发的并发症，涵盖眼内炎、类风湿关节炎与心内膜炎。而扁桃体培养检测结果显示存在念珠菌属（Candida sp.）、粪肠球菌（Enterococcus faecalis）及产气肠杆菌（Enterobacter aerogenes）。