Supplementary material: Systematic literature review and meta-analysis of cardiovascular risk factor management in selected Asian countries

These are peer-reviewed supplementary materials for the article 'Systematic literature review and meta-analysis of cardiovascular risk factor management in selected Asian countries' published in the Journal of Comparative Effectiveness Research.Table S1: Queries used for searching PubMed, EMBASE, and IMSEAR.Table S2: PICOS Criteria.Table S3: Definitions of hypertension, dyslipidemia, and diabetes mellitus by the authors of included studiesTable S4: Definitions of awareness, treatment, and control rate by the authors of included studiesTable S5: Risk assessment of the studies included in the SLRFigure S1: Funnel plot for awareness rateFigure S2: Funnel plot for treatment rateFigure S3: Funnel plot for control rate among those with the risk factor of interestFigure S4: Funnel plot for control rate among those being treatedPRISMA ChecklistAim: There is a need to understand the management status of hypertension, dyslipidemia/hypercholesterolemia, and diabetes mellitus in the Asia–Pacific region (APAC). Methods: We conducted a systematic literature review and meta-analysis to summarize the awareness, treatment, and/or control rates of these risk factors in adults across 11 APAC countries/regions. Results: We included 138 studies. Individuals with dyslipidemia had the lowest pooled rates compared with those with other risk factors. Levels of awareness with diabetes mellitus, hypertension, and hypercholesterolemia were comparable. Individuals with hypercholesterolemia had a statistically lower pooled treatment rate but a higher pooled control rate than those with hypertension. Conclusion: The management of hypertension, dyslipidemia,and diabetes mellitus was suboptimal in these 11 countries/regions.