The impact of Tcf1/Lef1 deficiency and prostagladin E (PGE) treatment on leukemic stem cell (LSC) transcriptome
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https://www.ncbi.nlm.nih.gov/sra/SRP095102
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资源简介:
Comparison of trasncriptome bewteen control LSCs and Tcf1/Lef1 deficient LSCs, LSCs treated with DMSO, PGE1 or PGE2. Overall design: Lineage negative BM cells were isolated from control or Tcf1/Lef1-deficient mice, and retrovirally transduced with p210-BCR-ABL retrovirus twice (at 24 hr interval), and 48 hrs after isolation, Lin-c-Kit+ Sca1+GFP+ cells were sorted as LSCs. The LSCs established from control BM cells were treated with DMSO, 20µM PGE1 or 20 µM PGE2 for 6 hrs.
创建时间:
2017-09-17



