Geant4-DNA simulations using complex DNA geometries generated by the DnaFabric tool
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http://doi.org/10.17632/7m2pgc27sv.1
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资源简介：
This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2018)
Abstract
Several DNA representations are used to study radio-induced complex DNA damages depending on the approach and the required level of granularity. Among all approaches, the mechanistic one requires the most resolved DNA models that can go down to atomistic DNA descriptions. The complexity of such DNA models make them hard to modify and adapt in order to take into account different biological conditions. The DnaFabric project was started to provide a tool to generate, visualise and modify such c...
Title of program: DnaFabric
Catalogue Id: AEZV_v1_0
Nature of problem
Simulations implying DNA geometrical models often show limitations to support the huge number of DNA constituents. In order to allow users to build, visualise and perform calculations on detailed DNA models including hundreds of thousands of DNA elements, a dedicated framework is needed.
Versions of this program held in the CPC repository in Mendeley Data
AEZV_v1_0; DnaFabric; 10.1016/j.cpc.2016.02.019
本程序源自贝尔法斯特女王大学（1969-2018年）所持有的CPC程序库。摘要部分阐述了在研究放射性诱导的复杂DNA损伤时，根据方法的不同以及所需粒度级别，采用了多种DNA表示形式。在所有方法中，机制法需要最为精细的DNA模型，这些模型可以深入到原子级别的DNA描述。此类DNA模型的复杂性使得它们难以修改和调整，以适应不同的生物学条件。DnaFabric项目旨在提供一种工具，用于生成、可视化以及修改此类精细的DNA模型。标题：DnaFabric，目录ID：AEZV_v1_0
问题性质：在涉及DNA几何模型的模拟中，常常显示出支持大量DNA组成成分的局限性。为了使用户能够构建、可视化并对包含数十万个DNA元素在内的详细DNA模型进行计算，需要一个专门的框架。
CPC存储库中Mendeley数据所持有的此程序的版本：AEZV_v1_0；DnaFabric；10.1016/j.cpc.2016.02.019
提供机构：
doi.org
