Assessing the Diagnostic Metrics of Cutaneous Leiomyomas in Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Syndrome: an Observational Study

- Figure S1: Age-dependent Negative Predictive Value of Cutaneous Leiomyomas Absence in the Diagnosis of HLRCC - Figure S2: Fagan Nomogram based on Bayes Theorem - Supplementary Methods and STROBE Statement - Table S1. Demographic Characteristics of the Study Cohort and Reason for Referral (n= 118) - Table S2. Demographics and Clinical Characteristics of the HLRCC Cohort (n= 68) - Table S3: Demographics and Clinical Characteristics of FH GPV Carriers with no CL (n= 5) and FH GPV Non-Carriers with CL (n= 1)- 图S1：无皮肤平滑肌瘤（Cutaneous Leiomyomas）对遗传性平滑肌瘤病和肾细胞癌综合征（HLRCC）诊断的年龄依赖性阴性预测值（Negative Predictive Value） - 图S2：基于贝叶斯定理（Bayes Theorem）的法戈诺模图（Fagan Nomogram） - 补充方法与STROBE声明（STROBE Statement） - 表S1：研究队列（Study Cohort）的人口统计学特征与转诊原因（n=118） - 表S2：HLRCC队列的人口统计学与临床特征（n=68） - 表S3：无皮肤平滑肌瘤的延胡索酸水合酶生殖系致病变异（FH GPV）携带者（n=5）与伴皮肤平滑肌瘤的FH GPV非携带者（n=1）的人口统计学与临床特征