Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Georg et al

In addition to the Figures published in the original article and associated supplemental Figures, the attached files contain the following information:
Mendeley Data 1-4
• Members of the PA-COVID-19 Study group
• Mendeley Data 1: a reanalysis of a published scRNA-seq data set of bronchoalveolar lavage (BAL) samples from COVID-19 patients and patients with non-COVID-19 pneumonia (Wauters et al., 2021) to investigate T cells and their phenotypes from the lung .
• Mendeley Data 2: Gating strategy and represantative plots of Figure S1
• Mendeley Data 3: Gating strategy and represantative plots of Figure 5D
• Mendeley Data 4: Gating strategy Firgures 5F/G/H

Supplementary Tables 1-6
• Supplementary Table 1: Cohort details related to Figures 1-6.
• Supplementary Table 2: Gene lists for the signatures “Response to Type I Interferon” , “Defense Response to virus” and “Cytotoxicity” used for GSEA, related to Figure 2 and Figure S3.
• Supplementary Table 3: Antibody panel “MCFC cohort 2” , related to Figure S1 and STAR Methods
• Supplementary Table 4: Antibody panel “degranulation assays” , related to Figures 3C-E.
• Supplementary Table 5: Antibody panel for “C3a binding capacity” , related to Figure 5D.
• Supplementary Table 6: Antibody panel “SARS-CoV-2 reactivity” , related to Figure 3F.

Gene list Annotation for scRNA sequencing

此外，除原文及其关联补充图表之外，所附文件包含以下信息：
Mendeley 数据 1-4
• PA-COVID-19 研究组成员
• Mendeley 数据 1：对一篇已发表的 scRNA-seq 数据集的重新分析，该数据集来源于 COVID-19 患者和非 COVID-19 肺炎患者的支气管肺泡灌洗 (BAL) 样本（Wauters 等人，2021年），旨在探究肺部的 T 细胞及其表型。
• Mendeley 数据 2：图 S1 的门控策略及代表性图表
• Mendeley 数据 3：图 5D 的门控策略及代表性图表
• Mendeley 数据 4：图 5F/G/H 的门控策略图表
补充表格 1-6
• 补充表格 1：与图 1-6 相关的队列详细信息。
• 补充表格 2：用于 GSEA 的“对 I 型干扰素反应”、"防御病毒反应"和“细胞毒性”特征基因列表，与图 2 和图 S3 相关。
• 补充表格 3：“MCFC 队列 2”的抗体面板，与图 S1 和 STAR 方法相关。
• 补充表格 4：“脱颗粒实验”的抗体面板，与图 3C-E 相关。
• 补充表格 5：“C3a 结合能力”的抗体面板，与图 5D 相关。
• 补充表格 6：“SARS-CoV-2 反应性”的抗体面板，与图 3F 相关。
scRNA 测序的基因列表注释