in vivo mRNA display: Large-scale Proteomics by Next Generation Sequencing
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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP272377
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资源简介:
We introduce in vivo mRNA display, a technology that converts a variety of proteomics applications into a DNA sequencing problem. Overall design: In vivo expressed proteins are coupled with their encoding mRNAs via a high-affinity stem-loop RNA binding domain interaction, enabling high-throughput identification of proteins with high sensitivity and specificity by next-generation DNA sequencing.
创建时间:
2020-10-20



