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Studying the heterogeneity of CAR-NK cells and their in vivo evolution after adoptive transfer from Mass cytometry profiling

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NIAID Data Ecosystem2026-03-14 收录
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http://flowrepository.org/id/FR-FCM-Z625
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资源简介:
Chimeric antigen receptor (CAR) engineering of natural killer (NK) cells is promising with early- phase clinical studies showing encouraging responses. However, the transcriptional signatures that control the fate of CAR-NK cells after infusion and factors that influence tumor control remain poorly understood. We performed single-cell mass cytometry to study the heterogeneity of CAR-NK cells and their in vivo evolution after adoptive transfer, from the phase of tumor control to relapse.
创建时间:
2023-01-01
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