X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine

X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine Descriptor: (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, QdtB Authors: Thoden, J.B, Holden, H.M. Deposit date: 2009-01-08 Release date: 2009-02-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose. Biochemistry, 48, 2009

热解糖嗜热杆菌（T. thermosaccharolyticum）QdtB与磷酸吡哆醛（PLP）:TDP-3-氨基奎诺糖醛亚胺复合物的X射线晶体结构。结构描述：(2R,3R,4S,5S,6R)-3,5-二羟基-4-{(1E)-[3-羟基-2-甲基-5-(膦酰氧基)甲基]吡啶-4-基亚甲基}氨基}-6-甲基四氢-2H-吡喃-2-基 [(2R,3S,5R)-3-羟基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基]甲基二氢二磷酸。作者：Thoden, J.B.、Holden, H.M.。入库日期：2009年1月8日。发布日期：2009年2月17日。最后修改日期：2023年9月6日。实验方法：X射线衍射（分辨率2.15埃）。引用文献：《Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose》，*Biochemistry*，2009年，第48卷。