RNA profiling changes of HDAC3 knockout AMs

NIAID Data Ecosystem2026-05-10 收录

肺泡巨噬细胞转录组

HDAC3基因敲除研究

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP367200 数据链接链接失效反馈

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资源简介：

HDAC3 is required for the maintenance of AM population and proper metabolism Overall design: Examination of transcriptome changes of control and HDAC3 knockout Aleolar macrophages from 6 week old mice.

创建时间：

2025-12-31

Cigarette smoking alters mRNA expression in human alveolar macrophages

吸烟相关基因

肺泡巨噬细胞转录组

Alveolar macrophages from never smokers and active smokers were isolated by bronchoalveolar lavage and gene expression was measured. Chronic cigarette smoke exposure, as occurs in smoker's lungs, lead

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Data expression in alveolar macrophages induced by lipopolysaccharide in humans

肺泡巨噬细胞转录组

LPS诱导免疫应答

Rationale: Lipopolysaccharide (LPS) is ubiquitous in the environment. Inhalation of LPS has been implicated in the pathogenesis and/or severity of several lung diseases, including pneumonia, chronic o

NIAID Data Ecosystem50

Transcriptome mapping of alveolar macrophages developing under Scgb1a1 deficiency.. Transcriptome mapping of alveolar macrophages developing under Scgb1a1 deficiency.

肺部免疫调节

肺泡巨噬细胞转录组

Alveolar macrophage (AM) is a mononuclear phagocyte key to the defense against respiratory infections. To understand AM’s role in airway disease development, we examined the influence of Secretoglobin

NIAID Data Ecosystem30

Mus musculus Transcriptome or Gene expression

流感病毒免疫应答机制

肺泡巨噬细胞转录组

To clarify the mechanism of NLRP3 in ImAT2 cells during IAV infection, ImAT2 cells were separated from the lung of Spc creERT2+/-; R26RtdEyfp and Spc creERT2-/-; R26RtdEyfp; Nlrp3fl/fl mice infected f

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Alveolar Macrophage Transcriptional Programs are Associated with Ventilator-Free Days in Acute Respiratory Distress Syndrome

急性呼吸窘迫综合征免疫学

肺泡巨噬细胞转录组

Rationale: Serial measurements of genome-wide transcriptional changes in alveolar macrophages (AMs) in patients with acute respiratory distress syndrome (ARDS) could identify dynamic biologic processe

NIAID Data Ecosystem50

RNA profiling changes of HDAC3 knockout AMs

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