Additional file 1 of Potential drug targets for asthma identified through mendelian randomization analysis
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Supplementary Material 1: Supplementary tables. Table S1.Genetic instruments of plasma and brain proteins for MR analysis. Table S2. Genetic instruments of asthma for bidirectional MR.Table S3. Heterogeneity analysis on proteins with two or more instruments.Table S4. Previously-reported genome-wide significant association of SNPs as genetic instruments of seven potential causal proteins.Table S5. Medications for asthma and their corresponding drug targets.Table S6. Current medications targeting seven potential causal proteins and interacted proteins.Table S7. Colocalization analysis of seven potential causal proteins and asthma.Table S8. Genetic instruments of seven potential causal proteins for external validation.
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2025-01-14
