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Testing rescue of AR signaling by ectopic expression of mutant AR allele in the presence of MDV-3100

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NIAID Data Ecosystem2026-03-11 收录
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Genetically engineered LNCaPs overexpressing various AR alleles were treated with 0.1% DMSO or 10uM MDV3100 for 24h prior to collection This experiment is designed to see if expressing the F876L/T877A mutant AR can rescue AR signaling in the presence of MDV3100 Engineered lines were seeded in 6-well plates for 3d with 100ng/ml doxycycline prior to treatment with 0.1% DMSO or 10uM MDV3100 for 24h

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2019-03-25
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